Table 3a.

Antidepressants

GENERIC AUS US UK Canada, Sth Africa, etc. Europe/Other Class
amitriptyline
R
Tryptanol; Elavil; Endep; Amitrol Elavil; Endep; Emitrip Trytizol; Lentizol Levate: Novotriptyn (Can); Trepiline; Saroten (SA) Adepril tricyclic
amoxipine H - Asendin Ascendis heterocyclic
bupropion
H R
- Wellbutrin - heterocyclic
citalopram Cipramil - Cipramil SSRI
clomipramine
H R
Anafranil; Placil Anafranil Anafranil tricyclic
desipramine
H
Pertofran Norpramin Pertofran Pertofrane(Can) Nortimil tricyclic
dibenzepine - - - Noveril (SA) tricyclic
dothiepin
Prothiaden; Dothep - Prothiaden dosulepin; Thaden; Jardin (SA) tricyclic
doxepin
H R
Sinequan; Deptran Sinequan; Adapin; Zonalon Sinequan Triadaprin (Can) tricyclic
fluoxetine
H R
Prozac; Lovan; Zactin; Erocap; Prozac Prozac Lorien (SA) SSRI
flupenthixol
H
- - Fluanxol thioxanthene¹
fluvoxamine
H R
Luvox, Faverin Luvox Faverin Fevarin, Maveral SSRI
hypericum perforatum St John's Wort St John's Wort St John's Wort herb
imipramine
H R
Tofranil Janimine; Norfranil; Tofranil; Tipramine Tofranil Impril; Novapramine (Can); Ethipramine; Panpramine; Miprilin (SA) tricyclic
isocarboxazid N - - Marplan MAOI
lofepramine
- - Gamanil Emdalen (SA) tricyclic
l-trytophan N l-trytophan l-tryptophan l-tryptophan; Optimax amino acid
serotonin precursor
maprotiline H - Ludiomil Ludiomil heterocyclic
mianserin Tolvon; Lerivon; Lumin ? Bolvidon Lantanon (SA) tetracyclic
mirtazapine
R N
Avanza, Remeron Remeron heterocyclic
moclobemide
H
Aurorix; Arima; Mohexal - Manerix RIMA
nefazodone
H
Serzone Serzone Dutonin heterocyclic
nortriptyline
H R
Allegron Aventyl; Pamelor Allegron; Aventyl tricyclic
paroxetine
H R
Aropax, Lumin Paxil Seroxat SSRI
phenelzine
H
Nardil Nardil Nardil MAOI
protriptyline - Vivactil Concordin Triptil (Can) tricyclic
quilonium SR Lithium Carbonate SR
reboxetine - Edronax selective noradrenaline upt. inhib.
sertraline
H R
Zoloft Zoloft Lustral SSRI
tranylcypromine
H
Parnate Parnate Parnate MAOI
trazadone
H R
- Desyrel; Trazon; Trialodine Molipaxin heterocyclic
trimipramine
H
Surmontil Surmontil Surmontil Rhotrimine; Apo-Trimip (Can); Tydamine (SA) tricyclic
tryptophan see l-tryptophan amino acid
venlafaxine
H R
Efexor Effexor Efexor heterocyclic; SNRI
viloxazine - - Vivalan heterocyclic
²amitriptyline + chlordiazepoxide - Limbitrol - Limbitrol(SA) tricyclic + benzodiazepine
²amitriptyline + perphenazine - Etrafon; Triavil Triptafen tricyclic + phenothiazine
²nortriptyline + fluphenazine N - - Motipress; Motival tricyclic + phenothiazine

See also:
"Treatment of Depression:" Tricyclics; MAOIs; SSRIs ; at Norfolk Mental Health Care.


Notes

¹ This is an antipsychotic agent with antidepressant properties. (See "Antipsychotics")
² These compounds combine amitriptylline with an anti-anxiety drug or an antipsychotic.
More common practice is to use separate agents if necessary.
SNRI = Selective Noradrenaline Reuptake Inhibitor.
SSRI = Selective Serotonin Reuptake Inhibitor.
RIMA = Reversible Inhibitor of Monoamine Oxidase.
Terminology: The mode of action of many antidepressants is not completely understood. While some classes are named via their putative action (SSRIs, MAOIs), other are named after the shape of their molecules (tricyclic, tetracyclic). Some of the new unclassified ones are labelled "heterocyclics", as per Basic and Clinical Pharmacology: Bertram G. Katzung, Appleton & Lange, Norwalk, 1995. This table follows that scheme.

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Drug Index

1st Ed. Nov 1997
Copyright 1997 Raymot